We record the NO-AD and NO-Age Seminar Series to enable a world-wide audience over the Internet, and to make available for viewers to watch at their convenience. All the videos recorded are with permission from the speakers. The speakers retain their copyright on the PPTs. Viewers are not allowed to use any of the PPTs for any public or private uses until a permission from the owner/speaker is obtained.
09th June 2020: Lecture by Prof. Jürgen Götz on ‘Alzheimer’s disease: Novel tau-based mechanisms and ultrasound-based therapeutic interventions’, University of Queensland, Australia.
16th June 2020: Lecture by Prof. Farrukh A. Chaudhry on ‘Glutamine transporters and their involvement in neuronal signalling and synaptic plasticity’, The University of Oslo, Oslo, Norway.
22nd June 2020: Lecture by Prof. Mark P. Mattson on ‘The impact of intermittent bioenergetic challenges on brain and body health’, The Johns Hopkins University, Baltimore, USA
Video (from 06:30)
Lecture by Asso. Prof. Evandro F. Fang on ‘增齡的10個分子生物學機制及其在促進健康長壽中的應用 The 10 hallmarks of ageing and their applications in healthy longevity‘, UiO, Oslo, Norway.
Video 1 (lecture in Chinese, with slides in English)
Video 2: An English version in ARDD2020 meeting
Video 3: BBB meeting in the U. of Bergen
Video 4: 2021-06-16 talk at the Hong Kong-Nordic Research network meeting –here
Video 5: 2021-11-06 talk at the Si-chuan Ageing meeting (in Chinese) here
Video 6: a 20-min talk here
Video 7: talk in the National University of Singapore on NAD+ (here)
14th July 2020: Lecture by Dr. Liu Shi on ‘Blood Proteomic Biomarkers for Alzheimer’s disease‘ from The University of Oxford, UK .
24th Sep 2020: Lecture by Prof. Jose M. Estrela on ‘Is it possible to contorl the progression of ALS?’ from the University of Valencia, Spain.
28th Oct 2020: Lecture by Prof. Nadia Raffaelli, on ‘NAD biosynthesis: behind the need of a redox coenzyme’, Polytechnic University of Marche, 60131- Ancona, Italy
Video (to start from 13:30 min)
30th Oct 2020: Lecture by Assistant Prof. Bo-jun Chen on ´Melatonin promotes sleep by activating the BK channel´, The University of Connecticut School of Medicine ( USA)
Video (to start from 15:35 min)
10th Nov 2020: Lecture by Prof. Malene Hansen on “Cellular recycling: Role of autophagy in aging and disease”, Sanford Burnham Prebys Medical Discovery Institute, USA
Video (to start from 2:00 min)
23rd Nov 2020: Lecture by Associate Prof. Joseph Baur, on ‘Tracing and manipulating NAD+ metabolism in cells and michondria’, from the University of Pennsylvania, USA
25th Nov 2020: The 1st NO/AD network meeting features 4 key note speakers with topics covering molecular mechanisms, clinical treatment, biomarkers, and longitudinal cohorts, as well as short talks from 36 laboratories in Norway.
Video 1 (morning session)
Video 2 (afternoon session 1)
Video 3 (afternoon session 2, partially missing due to technical issues)
14th Jan 2021: Lecture by Prof. Changning Wang, on ‘Molecular imaging of NAD+-dependent deacetylase SIRT1 in the brain’, from Harvard Medical School, USA
01st Feb 2021: The NO-Age and NO-AD Seminar Series 029: ‘Genetic dissection of neurodegenerative disease’ (tentative) by Prof John Hardy (Chair of the Molecular Biology of Neurological Disease) UCL Queen Square Institute of Neurology, UK; and ‘Pathophysiological propagation of tau: from cell-to-cell transfer to seeding of pathology; how do we move forward?’ by Dr. Simon Dujardin, Harvard Medical School, USA
08th Feb 2021: The NO-Age and NO-AD Seminar Series 021: ‘Anatomical Biology as a Key into Alzheimer’s Disease and Cognitive Aging’, by Prof. Scott A. Small, Columbia University, and ‘Impact of tau on vascular function in Alzheimer’s disease’ by Dr. Rachel Bennett, Massachusetts General Hospital and Harvard Medical School, USA
15th Feb 2021: Lecture by Prof. Brian Kennedy, on ‘Molecular Mechanisms of ageing and strategies to extend healthy longevity’, from University of Singapore, Singapore.
22nd Feb 2021: Lectures by Profs. Jackie Han on ‘Heterogeneity of Aging in human population’ and David Gems on ‘What is ageing? Lessons from C. elegans’.
04th March 2021: Lecture by Dr. Asgeir Kobro-Flatmoen on ‘Why talk about entorhinal cortex when we talk about Alzheimer’s disease?’.
08th March 2021: Lectures by Prof. Bjorn Schumacher on ‘Genome stability in ageing and disease: new perspectives from C. elegans’, from University of Cologne, Germany, and Prof. Shin-Ichiro Imai on ‘NMN in health and ageing’ from Washington University School of Medicine, USA
15th March 2021: Lecture by Prof. Han-Ming Shen on ‘Mechanisms of mitophagy and its roles in health and disease’, University of Macau, China
22th March 2021: The NO-Age and NO-AD Seminar Series 032 ‘C. elegans as a tool for industrial drug discovery in ageing, microbiome and neurodegenerative disease’
29th March 2021: Lecture by Prof. Christian Gonzalez-Billault on ‘GERO, a Chilean ageing Center focused on brain functions’, at the University of Chile, Chile.
12th April 2021: Lecture by Asso. Prof. Morten Scheibye-Knudsen on ‘Modulating DNA repair for healthy ageing’, at the University of Copenhagen, Denmark.
19th April 2021: Lectures by Prof. Dietmar Thal on ‘Amyloid and tau pathology in AD: neuropathology in symptomatic and presymptomatic cases’, and Assos. Prof. Wolfdieter Springer on ‘Selective mitochondrial autophagy in health, ageing, and neurodegeneration’.
26th April 2021: ‘Complement signaling and lipid metabolism in neuroinflammation and Alzheimer’s disease’ by Prof. Hui Zheng, Baylor College of Medicine, USA
03rd May 2021: ‘Cellular stress responses, signals, sensors, and outcomes’ by Prof. Simon Bekker-Jensen, University of Copenhagen, Denmark.
Video
10th May 2021: ‘Searching for anti-aging drugs and anti-aging mechanisms’ by Prof. Richard Miller, University of Michigan, and ‘Late life interventions to extend health and lifespan in mice’ by Dr. Sarah Mitchell, ETH Zurich.
Dr. Steven Zuryn
07th June 2021: ‘Mitochondrial genome mosaicism and resistance to damage’ by Dr. Steven Zuryn, The University of Queensland, Australia.
Prof. Dr. Adam Antebi
14th June 2021: ‘Convergent mechanisms of longevity’ by Prof. Dr. Adam Antebi, Max Planck Institute for Biology of Ageing, Cologne, Germany
Video
Prof. Dr. Ira Haraldsen
28th June 2021: ‘ AI-Mind – Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment’
Prof. Dr. Vilhelm Bohr
16th June 2021: ‘DNA damage and mitochondrial dysfunction in neurodegeneration and ageing: intervention with NAD supplementation’ by Dr. Vilhelm A. Bohr, National Institute on Ageing, USA and The University of Copenhagen, Denmark. This was the talk in the ‘Hong Kong-Nordic Research Network’ annual meeting: https://noage100.com/2021/06/23/success-of-the-1st-hong-kong-nordic-research-network-zoom-meeting/
Video
Assistant Prof. Nuo Sun and Assistant Prof. Bin Xu
06th Sep 2021: ‘Mitophagy in Physiological and Pathophysiological Conditions’ and ‘Small Molecule Modifiers of Toxic Protein Aggregation in Aging and Neurodegenerative Diseases’
Video (video will be uploaded later once the paper from one speaker is published)
Dr. Jane Reznick
20th Sep 2021: ‘Molecular insights into cardiometabolic health from a long-lived mammal the naked mole-rat‘
Prof. Hong Zhang
04th Oct 2021: ‘C. elegans autophagy’ by Prof. Zhang, Chinese Academy of Sciences, China
Prof. Alexander Clarke and Prof. Jo Poulton
15th Oct 2021: ‘Autophagy and inflammation in ageing and diseases’ by Prof. Alexander Clarke, The Kennedy Institute of Rheumatology, Oxford, UK. ‘Mitophagy and mitochondrial dynamics in mitochondrial diseases’ by Jo Poulton, Nuffield Department of Woment’s & Reproductive healthy, Oxford, UK
Prof. Michela Gallagher
18th Oct 2021: ‘ The Background on Treatment and Prevention of Cognitive Impairment in Aging and Progression to Alzheimer’s Dementia by Targeting Excess Neural Activity’ by Prof. Michela Gallagher, Johns Hopkins University, US
25th Oct 2021: ‘Mechanisms of Mitochondrial inheritance and radiation-induced Bystander Effects’ by Prof. Ding Xue, University of Colorado Boulder, USA
08th Nov 2021: ‘In vivo 31P magnetic resonance spectroscopy based NAD assay for noninvasively studying brain NAD metabolism and redox state during aging and neurodegeneration’ (tentative) by Prof. Wei Chen , University of Minnesota, USA
11th Nov 2021: ‘The Pathogenesis of the Metabolic Syndrome in the Elderly‘ by Prof. Kitt Petersen, Professor of Medicine (Endocrinology), Yale School of Medicine, USA
15th Nov 2021: ‘Immune cell crosstalk in the pathogenesis of Alzheimer’s disease’ by Prof. Gabriela Constantin, University of Verona, Italy
6th Dec 2021: ‘C. elegans surveillance of conserved cellular components in regulation of aging and pathogen defense’ by Prof.Gary Ruvkun, Harvard Medical School, USA
Prof. Jose M. Estrela
8th Dec 2021:‘ The Link between Oxidative Stress, Redox Status, Bioenergetics and Mitochondria in the Pathophysiology of ALS‘ by Prof. Jose M. Estrela, Department of Physiology, University of Valencia, Spain
7th Feb 2022: ‘Understanding neural networks in the entorhinal cortex of the normal brain‘ by Prof. Edvard Moser, NTNU, Norway
7th March 2022:’ Excessive alcohol misuse and accelerated brain aging- A metabolic perspective’ by Dr. Kim Hei-Man Chow, Chinese University of Hong Kong, China
Dr. Qian Cai and Dr. Jonathan T Pierce
28th March 2022: ‘Axonal transport and mitophagy regulation in Alzheimer’s disease by Dr. Qian Cai, University of Rutgers, USA. ‘Huge hints from a tiny worm: Preventing neurodegeneration in Alzheimer’s disease by Dr. Jonathan T Pierce, The University of Texas, USA
18th April 2022: ‘Mechanistic exploration of Alzheimer’s disease using iPSC techniques’ by Prof. Christopher D Link, University of Colorado, USA
25th April 2022: ‘Alzheimer’s Disease – A human-centric approach’ by Prof. Zameel Cader, The University of Oxford, UK
09th May 2022: ‘ Why a little bit of stress is good for you: Understanding how early-life interventions promote protein homeostasis and healthy tissue function later in life’ by Dr. Johnathan Labbadia, UCL, UK
06th June 2022:‘Modeling microbe-host interaction in the neurodegenerative disease’ by Dr. Chaogu Zheng, School of Biological Sciences, The University of Hong Kong, China
20th June 2022:’Astrocytes, sleep, and Alzheimer’s disease’ by Prof. Rune Enger, Institute of Basic Medical Sciences, UiO, Norway
05th Sep 2022: ‘Harnessing Endophenotypes and Network Medicine for Discovery of Pathobiology and Drug Repurposing in Alzheimer’s Disease’ by Dr. Feixiong Cheng, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, U.S
Prof. Isabel Beerman
06th Sep 2022: ‘Integrated epigenomics reveal dysregulated chromatin landscapes in aged hematopoietic stem cells underlying aberrant transcription’ by Prof. Isabel Beerman, Translational Gerontology/Epigenetics and Stem Cell Aging Unit, NIA, U.S
12th Sep 2022: ‘Use of genetically modified large animals to investigate neurodegenerative diseases’ by Prof. Xiaojiang Li, GHM Institute of CNS Regeneration, Jinan University, China. ‘Mechanisms of Alzheimer’s disease: focusing on genetics and microbiota’ by Prof. Cornelia Van Duijn, Nuffield Department of Population Health, University of Oxford, UK
19th Sep 2022:’Mitophagy as an anti-ageing pathway’ by Prof. Viktor Korolchuk, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, U.K
26th Sep 2022:’Autophagy in neurons, from development of aging’ by Prof. Patricia Boya, Centro de Investigaciones Biologicas (CIB), CSIC, Spain
06th Oct 2022: ‘Imaging and electrophysiology of sleeping mice – experimental tools at GliaLab’ by Prof. Rune Egner, Institute of Basic Medical Sciences, UiO, Norway
18th Oct 2022: ‘Post-transcriptional regulation of gene expression in Caenorhabditis elegans’ by Prof. KUROYANAGI, Hidehito, University of the Ryukyus Graduate School of Medicine, Okinawa, Japan
24th-25th Oct 2022: ‘The Nordic Centre Biennial Meeting on Global ageing and related healthcare challenges‘
Prof. Lucasz M. Ciesla
NO-AD 